Colonic Mucormycosis In A Post Covid Patient: A Case Report
Abstract
Mucormycosis is rare infection caused by fungi of order Mucorales which frequently involves rhino-cerebral or respiratory system with involvement of gastrointestinal (GI) tract being rare.Classically majority of patients with invasive mucormycosis are immunocompromised and/or have poor glycemic control. This happens especially during recovery phase of COVID-19 when patients are immunocompromised and simultaneously having poor glycemic control. While gastrointestinal (GI) mucormycosis is rare, stomach and colon are most commonly affected organs, and mortality can be as high as 85%.
Diagnosis is difficult since signs and symptoms, imaging and intraoperative gross appearance may not suggest mucormycosis. Diagnosis is usually by histopathologic identification of fungal hyphae in biopsy specimen. A high index of suspicion is therefore necessary in post-COVID-19 patients presenting with mesenteric ischemia or bowel perforation especially if they were immunocompromised. Here we present a case of post COVID disseminated mucormycosis in a 59-year-old diabetic male patient.
References
2. Roden MM, Zaoutis ET, Buchanan WL et al (2005) Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis 41:634–653
3. Zhang, J.-J.; Dong, X.; Cao, Y.-Y.; Yuan, Y.-D.; Yang, Y.-B.; Yan, Y.-Q.; Akdis, C.A.; Gao, Y.-D. Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China. Allergy 2020, 75, 1730–1741.
4. Recalcati, S. Cutaneous manifestations in COVID-19: A first perspective. J. Eur. Acad. Dermatol. Venereol. 2020, 34, e212–e213.
5. Ghuman SS, Sindhu P, Buxi TBS, et al.: CT appearance of gastrointestinal tract mucormycosis . Abdom Radiol (NY). 2021, 46:1837-1845
6. Chander J, Kaur M, Singla N, et al.: Mucormycosis: battle with the deadly enemy over a five-year period in India. J Fungi (Basel). 2018, 4:46.
7. Skiada A, Pavleas I, Drogari-Apiranthitou M: Epidemiology and diagnosis of mucormycosis: an update. JFungi (Basel). 2020, 2:265.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright and Open Access Policy
This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge.
JSSN applies the Creative Commons Attribution (CC BY) license to all works we publish. Under the CC BY license, authors retain ownership of the copyright for their article, but authors allow anyone to download, reuse, reprint, distribute, and/or copy articles in JSSN, so long as the original authors and source are cited. No permission is required from the authors or the publishers.
Article by JSSN is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at http://www.jssn.org.np/index.php?journal=jssn.
