Relevance of leucocytosis and neutrophilia in diagnosing appendicitis.
AbstractIntroduction: The diagnosis of appendicitis is based on clinical history, abdominal ! ndings, blood and radiological investigations. The study was conducted to see the relevance of pre operative leucocytosis and neutrophilia in histopathological proven cases of appendicitis over a one year period.Materials and Methods: A retrospective study was conducted at Nepal Medical College Teaching Hospital on histopathologically proven cases of appendicitis from June 2009 up to May 2010. p value less than 0.05 was taken as signi! cant.Result: There were 85 cases of histopathologically proven cases of appendicitis. Based on history (migratory abdominal pain from periumilical region to right iliac fossa, nausea, vomiting, and fever) and abdominal examination (pain/tenderness in right iliac fossa, rebound tenderness), only 68 were clinically suggestive of appendicitis. Among them, pre operative leucocytosis and neutrophilia were seen in only 39 and 40 cases respectively. Out of 17 cases which were not clinically suggestive, leucocytosis and neutrophilia were seen in 5 and 6 cases respectively. In total, leucocytosis and neutrophilia were seen in 44 and 46 cases. The operative ! ndings were suggestive of appendicitis of varying degree in all cases. Radiological diagnosis was not taken in consideration.Conclusion: Clinical ! ndings of appendicitis do have a positive correlation with preoperative leucocytosis but not with neutrophilia.Key words: Appendicitis, leucocytosis, neutrophilia
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