An Assessment of Antimicrobial Prescription Pattern among Surgical Patients: A Hospital Based Cross Sectional Descriptive Study

  • Bikash Bahadur Rayamajhi Nepalese Army Institute of Health Sciences, Sanobharang, kathmandu
  • Anjan Khadka Assistant Professor, Department of Pharmacology, Nepalese Army Institute of Health Sciences (NAIHS), Sanobharyang, Kathmandu, Nepal
  • Santosh Khadka Assistant Professor, Department of Anesthesiology, Nepalese Army Institute of Health Sciences (NAIHS), Sanobharyang, Kathmandu, Nepal
  • Seejana Singh Maharjan Medical Officer, Shree Birendra Hospital, Chhauni, Kathmandu, Nepal

Abstract

Introduction  
Antimicrobials are used before, during and after surgery to prevent infections to decrease the duration of hospital stay, increase surgical outcomes and reduce health-related costs. There is inadequate evidence to determine the effective group of antimicrobials to be used in surgical prophylaxis in our settings.
 
Methods 
A hospital-based cross-sectional descriptive study involving antimicrobial prescriptions pattern among 223 surgical patients was undertaken. Information on patient’s demographic variables, diagnosis, type of surgery and wound, perioperative antimicrobial use, postoperative complications and number of antimicrobials prescribed from the essential medicine list were recorded. The antibiotic prescription patterns were assessed based on a comparison with international and national guidelines.
 
Results
 Among 223 patients, males were predominant with an overall mean age of 42.77 years. The total number of diagnoses was 30, the commonest being appendicitis (21.52%), urinary stone disease (15.69%), hernia (13.90%) and cholelithiasis (11.65%). The common surgeries performed were emergency appendectomy, hernioplasty and laparoscopic cholecystectomy. Eighteen types of drugs from seven different antimicrobial groups were used perioperatively, out of which 73% and 83% were prescribed based on international and national guidelines respectively.
 
Conclusion 
The most common antimicrobial used was third-generation cephalosporin. The postoperative antimicrobial rate was found higher compared to preoperative and intraoperative prescriptions and for a longer duration compared to national and international guidelines.

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Published
2021-12-13
How to Cite
RAYAMAJHI, Bikash Bahadur et al. An Assessment of Antimicrobial Prescription Pattern among Surgical Patients: A Hospital Based Cross Sectional Descriptive Study. J Soc Surg Nep, [S.l.], v. 24, n. 1, p. 23-27, dec. 2021. ISSN 2392-4772. Available at: <http://jssn.org.np/index.php?journal=jssn&page=article&op=view&path%5B%5D=383>. Date accessed: 28 jan. 2022.