Role of second transurethral resection in determining residual tumor in nonmuscle- invasive bladder cancer

  • Pukar Maskey Patan Academy of Health Sciences

Abstract

Abstract
Objective: To determine the rate of residual tumors after first transurethral resection of nonmuscle-invasive bladder cancer, and to determine the factors associated with the presence of residual tumors and upstaging of nonmuscle-invasive bladder cancer.
Materials and methods: This was a prospective observational study of 43 patients of bladder cancer who had a diagnosis of nonmuscle-invasive bladder cancer following an initial transurethral resection. Demographic data and data on tumor characteristics were obtained. Patients underwent a second transurethral resection within 2 to 8 weeks. Histopathological findings at first and second resection were compared.
Results: There were 20 patients with Ta tumor and 23 patiens with T1 tumor at initial resection. Residual tumor was detected in 18 (41.86%) patients overall, 2 in patients with Ta tumor (10%) and 16 in patients with T1 tumor (69.5%). Tumors with T1 stage, high grade, size more than 3 centimeters and sessile growth pattern were seen to have significant association with the presence of residual tumors. Six patients with T1 disease upstaged to T2 disease after second resection (26%), while there were no upstaging with Ta tumors. Tumors with T1 stage, sessile configuration and size more than 3 centimeters were found to be significantly associated with upstaging.
Conclusion: Nonmuscle-invasive bladder tumors with T1 stage, high grade, size more than 3 centimeters and sessile growth pattern are associated with the presence of residual tumor and upstaging in second transurethral resection. A second transurethral resection should be considered in patients with these tumor characteistics.
 
Key word: nonmuscle invasive bladder tumor, TURBT, second TURBT
Published
2018-07-12
How to Cite
MASKEY, Pukar. Role of second transurethral resection in determining residual tumor in nonmuscle- invasive bladder cancer. Journal of Society of Surgeons of Nepal (JSSN), [S.l.], v. 20, n. 2, p. 35-42, july 2018. ISSN 2392-4772. Available at: <http://jssn.org.np/index.php?journal=jssn&page=article&op=view&path%5B%5D=307>. Date accessed: 19 aug. 2018.
Section
Original Article